{"id":23669,"date":"2021-12-28T10:50:00","date_gmt":"2021-12-28T02:50:00","guid":{"rendered":"https:\/\/www.paiqinano.com\/?p=23669"},"modified":"2021-12-27T14:02:04","modified_gmt":"2021-12-27T06:02:04","slug":"%e4%b8%8e%e4%bb%80%e4%b9%88%e6%98%af%e5%8e%bb%e6%ba%b6%e5%89%82%e5%8c%96%ef%bc%9f%e4%b8%8e%e7%96%8f%e6%b0%b4%e6%95%88%e5%ba%94%e6%9c%89%e4%bb%80%e4%b9%88%e5%85%b3%e8%81%94","status":"publish","type":"post","link":"https:\/\/www.paiqinano.com\/?p=23669","title":{"rendered":"\u4e0e\u4ec0\u4e48\u662f\u53bb\u6eb6\u5242\u5316\uff1f\u4e0e\u758f\u6c34\u6548\u5e94\u6709\u4ec0\u4e48\u5173\u8054"},"content":{"rendered":"<p style=\"margin-top: 0px; margin-bottom: 0px; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px;\">\u5927\u4f19\u513f\u5e94\u5f53\u90fd\u4e86\u89e3\u4eb2\u6c34\u6027\u6548\u7528\uff08hydrophobic effect\uff09\uff0c\u5373\u6eb6\u6db2\u4e2d\u975e\u6781\u6027\u5206\u5b50\u6298\u53e0\u5f0f\u6216\u8d28\u5b50\u5316\u7684\u72b6\u51b5\uff0c\u8bf4\u5b9e\u8bdd\u4fbf\u662f\uff0c\u6cb9\u4e0e\u6c34\u4e0d\u76f8\u6eb6\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" title=\"1.png\" src=\"\/wp-content\/uploads\/2021\/12\/20211215134558-61b9f196a1576.png\" \/><\/p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px;\">\u4eb2\u6c34\u6027\u6548\u7528\u8bf4\u8d77\u6765\u975e\u5e38\u7b80\u5355\u5f62\u8c61\u5316\uff0c\u4f46\u5b83\u5219\u662f\u4e2a\u5fc3\u72e0\u624b\u8fa3\uff01\u4f8b\u5982\uff0c\u5728\u86cb\u6e05\u6298\u53e0\u5f0f\u3001\u836f\u54c1-\u86cb\u6e05\u76f8\u4e92\u5f71\u54cd\uff0c\u53ca\u86cb\u6e05-\u86cb\u6e05\u76f8\u4e92\u5f71\u54cd\u4e2d\uff0c\u4eb2\u6c34\u6027\u6548\u7528\u7ecf\u5e38\u662f\u5173\u952e\u6027\u539f\u56e0\u4e4b\u4e00\u5462[1]\uff01<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u8bf4\u5230\u758f\u6c34\u6027\u5728\u836f\u54c1-\u86cb\u6e05\u76f8\u4e92\u5f71\u54cd\u4e2d\u7684\u4e3b\u8981\u5371\u5bb3\uff0c\u5b9e\u9645\u4e0a\u7edd\u5927\u591a\u6570\u53d1\u552e\u7684\u5c0f\u5206\u5b50\u836f\u7269\u90fd\u662f\u6709\u4e00\u5b9a\u7684\u758f\u6c34\u6027[2]\u3002\u8bd5\u9a8c\u4e5f\u8868\u660e\uff0c\u4eb2\u6c34\u6027\u76f8\u4e92\u5f71\u54cd\u5bf9\u878d\u5408\u7684\u5949\u732e\u662f\u5341\u5206\u6781\u5927\u7684\uff0c\u53ef\u4ee5\u505a\u5230\u7ea630 cal \/ (mol\u00b7 ?)\u3002\u8fd9\u4e2a\u662f\u4ec0\u4e48\u7406\u5ff5\u5462\uff1f\u4f8b\u5982\uff0c\u52a0\u4e0a\u4e00\u4e2a\u7f9f\u57fa\uff08-CH3\uff09\u9020\u6210\u7684\u4eb2\u6c34\u6027\u76f8\u4e92\u5f71\u54cd\uff0c\u5bf9\u7ed3\u5408\u81ea\u7531\u80fd\u7684\u5949\u732e\u662f0.7kcal\/mol\uff0c\u6362\u53e5\u8bdd\u8bf4\u53ef\u4ee5\u63d0\u9ad83.5\u500d\u4e0a\u4e0b\u7684\u6d3b\u529b[1]!<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u4eb2\u6c34\u6027\u76f8\u4e92\u5f71\u54cd\u8fd9\u822c\u5e7f\u6cdb\u53c8\u8fd9\u822c\u5173\u952e\uff0c\u4f60\u662f\u5426\u4f1a\u5f88\u597d\u5947\uff0c\u5b83\u7684\u5b9e\u8d28\u7a76\u7adf\u662f\u4ec0\u4e48\uff1f\u55ef\uff0c\u5927\u5bb6\u4fbf\u662f\u8d4f\u6790\u8fd9\u7c7b\u8ffd\u5bfb\u7684\u7cbe\u795e\u5b9e\u8d28\uff01\u4eca\u65e5\uff0c\u6211\u5c31\u548c\u5927\u5bb6\u6df1\u6252\u4e00\u4e0b\u4eb2\u6c34\u6027\u76f8\u4e92\u5f71\u54cd\uff0c\u800c\u4e14\u8fd8\u4f1a\u7ee7\u7eed\u8c08\u5230\u4e8c\u53f7\u4e3b\u4eba\u516c\uff1a\u53bb\u6709\u673a\u6eb6\u5242\u5316\uff08Desolvation\uff09\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u8bf4\u5230\u5171\u4ef7\u952e\u6216\u662f\u79bb\u5b50\u952e\u7684\u5b9e\u8d28\uff0c\u53ef\u4ee5\u89e3\u91ca\u4e3a\u7535\u5b50\u4e91\u4e00\u5b9a\u7684\u7a0b\u5ea6\u7684\u904d\u5e03\u76f8\u53e0\u6216\u662f\u9759\u7535\u611f\u5e94\u76f8\u4e92\u5f71\u54cd\u3002\u53ef\u662f\uff0c\u4eb2\u6c34\u6027\u76f8\u4e92\u5f71\u54cd\u5374\u6ca1\u6cd5\u4ece\u539f\u5b50\u95f4\u7684\u529b\u6765\u4e86\u89e3\uff0c\u4f8b\u5982\u4f60\u65e0\u6cd5\u8868\u8ff0\u82ef\u73af\u4e0a\u7684\u4e00\u4e2a\u78b3\u539f\u5b50\u5230\u5e95\u662f\u5229\u7528\u54ea\u4e9b\u539f\u5b50\u95f4\u76f8\u4e92\u4f5c\u7528\u529b\u52fe\u5f15\u4e0a\u7f9f\u57fa\u7684\u78b3\u539f\u5b50\uff0c\u4ea7\u751f\u4eb2\u6c34\u6027\u76f8\u4e92\u5f71\u54cd\u7684\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u90a3\u9ebc\uff0c\u63a8\u52a8\u4eb2\u6c34\u6027\u76f8\u4e92\u5f71\u54cd\u7684\u5230\u5e95\u662f\u4f55\u8bb8\u4eba\u4e5f\u5462\uff1f<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u8bf4\u51fa\u6765\uff0c\u5b9e\u9645\u4e0a\u4e00\u70b9\u4e5f\u4e0d\u79d8\u5bc6\uff0c\u5b83\u4fbf\u662f\u201c\u71b5\u201d\uff08Entropic\uff09[3]\uff01\u6211\u4eec\u77e5\u9053\u5728\u63a7\u6e29\u6052\u538b\u7ba1\u7406\u4f53\u7cfb\u4e0b\u53ef\u4ee5\u7528\u5409\u5e03\u65af\u81ea\u7531\u80fd\uff08Gibbs Free Energy\uff09\u5206\u8fa8\u70ed\u5b66\u5168\u8fc7\u7a0b\u662f\u4e0d\u662f\u81ea\u53d1\u6027\uff0c\u5176\u65b9\u7a0b\u5f0f\u5982\u4e0b\u6240\u793a\uff1a<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u0394G=\u0394H?T\u0394S<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u8fd9\u4e00\u65b9\u7a0b\u5f0f\u4e5f\u6765\u53d9\u8ff0\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u7684\u878d\u89e3\u5168\u8fc7\u7a0b\uff0c\u5f53\u0394G&lt;0\u610f\u5473\u7740\u878d\u89e3\u5168\u8fc7\u7a0b\u81ea\u53d1\u6027\uff0c\u76f8\u53cd\u5219\u5e76\u4e0d\u662f\u3002\u8868\u8fbe\u5f0f\u4e2d\u0394H\u6307\u7113\u53d8\uff0c\u0394S\u6307\u7684\u662f\u71b5\u53d8\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u5b9e\u9645\u4e0a\u8fd9\u4e00\u65b9\u7a0b\u5f0f\u8fd8\u53ef\u4ee5\u7528\u4e8e\u53d9\u8ff0\u836f\u54c1\u5438\u9644\u548c\u86cb\u6e05\u7684\u76f8\u4e92\u5f71\u54cd\u5168\u8fc7\u7a0b\uff1a\u4e00\u5207\u7684\u836f\u54c1\u878d\u5408\u5168\u8fc7\u7a0b\u5b9e\u9645\u4e0a\u5168\u662f\u7113\u53d8\u548c\u71b5\u53d8\u7684\u4e00\u540c\u7d50\u679c\uff0c\u4ec5\u4ec5\u6211\u4eec\u5728\u4e86\u89e3\u878d\u5408\u5168\u8fc7\u7a0b\u65f6\u901a\u5e38\u5ffd\u89c6\u4e86\u71b5\u53d8\u7684\u529f\u6548\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u71b5\uff0c\u662f\u5565\u73a9\u610f\u513f\u5462\uff1f\u5b98\u65b9\u7f51\u754c\u5b9a\uff0c\u71b5\u662f\u7ba1\u7406\u4f53\u7cfb\u4e0b\u5168\u90e8\u5916\u90e8\u7ecf\u6d4e\u60c5\u51b5\u6570\u7684\u603b\u6570\u7684\u5f53\u7136\u5bf9\u6807\u503c\u4e58\u4e8e\u73bb\u5c14\u5179\u66fc\u5e38\u6570\u3002\u5bf9\u8fd9\u4e00\u754c\u5b9a\u4e0d\u660e\u767d\u4e5f\u6ca1\u4e8b\u513f\uff0c\u5927\u5bb6\u53ea\u5fc5\u987b\u4e86\u89e3\uff0c\u4ece\u6d3b\u5316\u80fd\u7684\u89c6\u89d2\uff0c\u5047\u5982\u67d0\u7c7b\u8f6c\u53d8\u4fc3\u4f7f\u7ba1\u7406\u4f53\u7cfb\u6709\u8d8a\u591a\u7684\u60c5\u51b5\u6570\uff0c\u5219\u6709\u76ca\u4e8e\u8fd9\u7c7b\u8f6c\u53d8\u7684\u81ea\u53d1\u6027\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u8fd4\u56de\u5927\u5bb6\u7684\u5438\u6c34\u529f\u6548\u4e0a\uff0c\u5982\u679c\u6211\u4eec\u5c06\u758f\u6c34\u6027\u7684\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u6254\u8fdb\u6c34\u91cc\uff0c\u90a3\u6d3b\u5316\u80fd\u600e\u6837\u8f6c\u53d8\u5462\uff1f\u6700\u5148\u6c34\u91cc\u539f\u672c\u7684\u5171\u4ef7\u952e\u4e92\u8054\u7f51\u53ef\u80fd\u88ab\u6bc1\u574f\u4ee5\u7a7a\u51fa\u4f4d\u7f6e\u7ed9\u758f\u6c34\u6027\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\uff0c\u8fd9\u662f\u4e00\u4e2a\u5438\u70ed\u53cd\u5e94\u5168\u8fc7\u7a0b\u3002\u968f\u540e\uff0c\u5728\u758f\u6c34\u6027\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u5468\u8fb9\uff0c\u6c34\u5206\u53ef\u80fd\u4ea7\u751f\u4e00\u4e2a\u76f8\u8fd1\u56da\u7262\u7684\u6784\u9020\uff0c\u4ea7\u751f\u66f4\u4e3a\u4e95\u7136\u6709\u5e8f\u7684\u5171\u4ef7\u952e\u3002<\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" title=\"2.png\" src=\"\/wp-content\/uploads\/2021\/12\/20211215134558-61b9f196d1bb0.png\" \/><\/p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px;\">\u5927\u5bb6\u7ec6\u60f3\u4e00\u4e0b\u4f1a\u53d1\u89c9\uff0c\u6574\u4e2a\u8fc7\u7a0b\u4e2d\u7684\u7113\u53d8\uff08\u0394H\uff09\u4e0d\u597d\u8bf4\u662f\u6b63\u3001\u8d1f\u6216\u662f\u76f8\u540c\u7684\uff0c\u7531\u4e8e\u65b0\u4ea7\u751f\u7684\u5171\u4ef7\u952e\u4e5f\u8bb8\u80fd\u8d54\u507f\u7b2c\u4e00\u6b65\u5207\u65ad\u7684\u5171\u4ef7\u952e\u7684\u52a8\u80fd\u3002\u53ef\u662f\uff0c\u758f\u6c34\u6027\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u5468\u8fb9\u66f4\u4e3a\u4e95\u7136\u6709\u5e8f\uff08\u7ed3\u6784\u578b\uff09\u7684\u6c34\u5206\u5c06\u4fc3\u4f7f\u7ba1\u7406\u4f53\u7cfb\u7684\u71b5\u53d8\uff08\u0394S\uff09\u51cf\u5c11\uff0c\u800c\u4e14\u8fd9\u4e00\u8f6c\u53d8\u901a\u5e38\u6bd4\u7113\u53d8\u7684\u8f6c\u53d8\u66f4\u9ad8\u3002\u4f9d\u636e\u5409\u5e03\u65af\u81ea\u7531\u80fd\u516c\u5f0f\u8ba1\u7b97\uff0c\u0394G=\u0394H?T\u0394S\uff0c\u8f83\u5c0f\u7684\u0394H\uff08\u6b63\u8d1f\u6781\u4e0d\u660e\uff09\u51cf\u6389\u4e00\u4e2a\u8d1f\u7684\u6bd4\u8f83\u5927\u7684\u0394S\uff0c\u8fd9\u4e00\u7d50\u679c\u662f\u6b63\u7684\uff0c\u610f\u5473\u7740\u7740\u758f\u6c34\u6027\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u6ca1\u6cd5\u81ea\u53d1\u6027\u7684\u878d\u89e3\u5230\u6c34\u91cc\u3002\u5f53\u758f\u6c34\u6027\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u96c6\u805a\u65f6\uff0c\u8fd9\u4e00\u96c6\u805a\u7684\u603b\u4f53\u4e0e\u6c34\u7684\u4e86\u89e3\u8868\u5c42\u6bd4\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u5f7b\u5e95\u5300\u79f0\u5206\u6563\u5316\u5728\u9971\u548c\u6eb6\u6db2\u4e2d\u7684\u4e86\u89e3\u9762\u5c0f\uff0c\u79d1\u5b66\u5316\u7684\u6c34\u5206\u964d\u81f3\u81f3\u5c11\uff0c\u968f\u610f\u7684\u3001\u6709\u5927\u91cf\u60c5\u51b5\u6570\u7684\u6c34\u5206\u505a\u5230\u8f83\u591a\uff0c\u4e0e\u6b64\u540c\u65f6\u71b5\u4e5f\u8f83\u5927\uff0c\u8fd9\u5c31\u662f\u4eb2\u6c34\u6027\u6548\u7528\u3002<\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" title=\"3.png\" src=\"\/wp-content\/uploads\/2021\/12\/20211215134558-61b9f196ee8db.png\" \/><\/p>\n<p>\u56fe\u4e2d\u8868\u660e\u4e0d\u4e00\u6837\u73af\u5883\u6e29\u5ea6\u4e0b\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u878d\u89e3\u7684\u7113\u53d8\u3001\u71b5\u53d8\u548c\u5409\u5e03\u65af\u81ea\u7531\u80fd\u8f6c\u53d8\u3002\u6a2a\u5750\u6807\u610f\u5473\u7740\u4e0d\u4e00\u6837\u6eab\u5ea6\u3002\u4e0b\u5de6\u56fe\u662fLJ\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u878d\u89e3\u5230MB\u6eb6\u6db2\u4e2d\u7684\u57fa\u7840\u7406\u8bba\u9884\u6d4b\u5206\u6790\u7d50\u679c\uff0c\u4e0b\u56fe\u662f\u4eb2\u6c34\u6027\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u878d\u89e3\u7684\u7814\u7a76\u7d50\u679c\u3002\u6a2a\u5750\u6807\u610f\u5473\u7740\u6eab\u5ea6\uff0c\u80fd\u591f\u770b\u89c1\u4e0d\u4e00\u6837\u73af\u5883\u6e29\u5ea6\u4e0b\u758f\u6c34\u6027\u7269\u8d28\u7684\u91cf\u6d53\u5ea6\u7684\u878d\u89e3\u5409\u5e03\u65af\u81ea\u7531\u80fd\u5168\u662f\u6b63\u7684\uff0c\u6362\u53e5\u8bdd\u8bf4\uff0c\u4e0d\u53ef\u4ee5\u81ea\u53d1\u6027\u878d\u89e3\u3002<\/p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px;\"><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u8fd4\u56de\u5c0f\u5206\u5b50\u836f\u7269\u4e0e\u86cb\u6e05\u76f8\u4e92\u5f71\u54cd\u7ba1\u7406\u4f53\u7cfb\u4e0a\uff0c\u5982\u4eca\u6709\u4e9b\u4eba\u8be2\u95ee\u4f60\uff0c\u4e3a\u4f55\u6dfb\u52a0\u758f\u6c34\u6027dna\u53ef\u4ee5\u63d0\u5347\u836f\u54c1\u5206\u5b50\u7ed3\u6784\u7684\u6d3b\u529b\u5462\uff1f\u7406\u89e3\u4e86\u5982\u4e0a\u6240\u8ff0\u7684\u653b\u7565\u5927\u5168\uff0c\u662f\u4e0d\u662f\u4f60\u5f88\u7b80\u5355\u5730\u5c31\u80fd\u627e\u5230\u7b54\u6848\uff1a\u7531\u4e8e\u758f\u6c34\u6027\u5b98\u80fd\u56e2\u8fdb\u5230\u758f\u6c34\u6027\u7684\u86cb\u6e05\u888b\u5b50\uff0c\u4fc3\u4f7f\u4ea7\u54c1\u7684\u758f\u6c34\u6027\u5b98\u80fd\u56e2\u5c3d\u91cf\u907f\u514d\u7684\u6cc4\u9732\u5728\u6eb6\u6db2\u4e2d\uff0c\u56e0\u6b64\u5c31\u4f7f\u7ba1\u7406\u4f53\u7cfb\u66f4\u4e3a\u5e73\u7a33\u8fdb\u800c\u63d0\u9ad8\u6d3b\u529b\u3002\u8fd9\u4e00\u56de\u5e94\u53ef\u4ee5\u7ed9100\u5206\u5427\uff1f^_^<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u53ef\u662f\u5462\uff0c\u8fd8\u6ca1\u5b8c\u6ca1\u4e86\uff0c\u5047\u5982\u6211\u8981\u544a\u8bc9\u4f60\uff0c\u4eb2\u6c34\u6027\u5b98\u80fd\u56e2\u4e0e\u4eb2\u6c34\u57fa\u56e2\u7684\u66f4\u6362\uff0c\u4e43\u81f3\u53ef\u4ee5\u8ba9\u6d3b\u529b\u8f6c\u53d84\u5343\u500d\uff0c\u4f60\u662f\u5426\u4f1a\u611f\u89c9\u96be\u4ee5\u60f3\u8c61\uff1f<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u6765\uff0c\u4e0d\u614c\uff0c\u5927\u5bb6\u518d\u6b21\u804a~ \u5c0f\u6545\u4e8b\u6216\u662f\u5f97\u4ece\u4eb2\u6c34\u6027\u6548\u7528\u8c08\u8d77\uff1a\u5728\u4e00\u4e9b\u7ba1\u7406\u4f53\u7cfb\u4e2d\uff0c\u758f\u6c34\u6027\u86cb\u6e05\u8868\u5c42\u7528\u4e00\u4e9b\u9002\u5408\u7684\u758f\u6c34\u6027\u5206\u5b50\u5360\u6709\uff0c\u5927\u5bb6\u53d1\u89c9\uff0c\u8fd9\u5bf9\u7ed3\u5408\u81ea\u7531\u80fd\u7684\u5949\u732e\u53ef\u4ee5\u505a\u5230\u597d\u591a\u4e2akcal\/mol [4]\uff01\u4f8b\u5982\u4e0b\u8fb9\u8fd9\u4e00\u4e8b\u4f8b\uff1a<\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" title=\"4.png\" src=\"\/wp-content\/uploads\/2021\/12\/20211215134559-61b9f19718cf2.png\" \/><\/p>\n<p>factor Xa\u548c\u5176\u7f13\u805a\u5242\u7684\u7ed3\u6676\u4f53\u6784\u9020\uff08PDB Code 2j4i\uff09<\/p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px;\">\u56fe\u4e2d\u662ffactor Xa\u548c\u5176\u7f13\u805a\u5242\uff08From GSK\uff09\u7684\u7ed3\u6676\u4f53\u6784\u9020\uff08PDB Code 2j4i\uff09\uff0c\u5176Ki\u662f1nM\uff0c\u53ef\u662f\u5047\u5982\u5c06\u56fe\u4f8b\u4e2d\u9ad8\u5c55\u793a\u7684\u5f02\u4e19\u57fa\u6362\u6210\u6c22\uff08H\uff09\uff0c\u5176\u6d3b\u529b\u7acb\u5373\u964d\u4f4e\u523039\u03bcM\uff0c\u6d3b\u529b\u7acb\u5373\u76f8\u8ddd\u4e864\u5343\u500d\uff01<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u56fe\u4e2d\u4e8b\u4f8b\u4e2d\u80fd\u591f\u770b\u89c1\uff0cTyr99\u3001Trp215\u548cPhe174\u6784\u6210\u7684\u758f\u6c34\u6027\u7684\u878d\u5408\u5185\u8154\uff0c\u6839\u636e\u914d\u4f4d\u4e0a\u7684\u5f02\u4e19\u57fa\u4ea7\u751f\u4eb2\u6c34\u6027\u76f8\u4e92\u5f71\u54cd\uff0c\u8fdb\u800c\u63d0\u5347\u6d3b\u529b\u3002\u53ef\u662f\u8fd9\u4e00\u6b21\uff0c\u4e0d\u63d0\u5219\u5df2\uff0c\u4e00\u63d0\u4fbf\u662f\u4ee4\u4eba\u9707\u60ca\u76844\u5343\u500d\uff01\u8fd9\u662f\u4e3a\u4ec0\u4e48\u5462\uff1f<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u8bf4\u8d77\u6e05\u6670\u8fd9\u4e2a\u95ee\u9898\uff0c\u5c31\u5f97\u8bf7\u51fa\u4eca\u65e5\u7684\u4e8c\u53f7\u4e3b\u4eba\u516c\uff0c\u4e5f\u662f\u5927\u4f19\u513f\u5728\u836f\u54c1\u8bbe\u8ba1\u65b9\u6848\u4e2d\u975e\u5e38\u5bb9\u6613\u5ffd\u89c6\u7684\uff0c\u53bb\u6709\u673a\u6eb6\u5242\u5316\u6548\u7528\uff08desolvation\uff09\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u5982\u4e0b\u56fe\u6e05\u695a\u7684\u53d9\u8ff0\u4e86\u8be5\u5168\u8fc7\u7a0b\uff0c\u836f\u54c1\u5206\u5b50\u7ed3\u6784\u5728\u6eb6\u6db2\u81ea\u7136\u73af\u5883\u91cc\u8fdb\u5230\u9776\u70b9\u86cb\u6e05\u878d\u5408\u5185\u8154\u7684\u73af\u8282\u4e2d\uff0c\u5fc5\u987b\u6446\u8131\u539f\u5148\u7684\u6c34\u73af\u5883\uff0c\u800c\u4e14\u5c06\u9776\u70b9\u878d\u5408\u888b\u5b50\u4e2d\u7684\u6c34\u6392\u51fa\u6765\uff0c\u8fd9\u4e00\u73af\u8282\u4e2d\u635f\u8017\u6216\u5f97\u5230\u7684\u52a8\u80fd\u4fbf\u662f\u53bb\u6709\u673a\u6eb6\u5242\u5316\u80fd\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" title=\"5.png\" src=\"\/wp-content\/uploads\/2021\/12\/20211215134559-61b9f1973500a.png\" \/><\/p>\n<p>\u5728\u6c34\u73af\u5883\u4e2d\u836f\u54c1\u5206\u5b50\u7ed3\u6784\u8fdb\u5230\u86cb\u6e05\u878d\u5408\u5185\u8154\u7684\u5168\u8fc7\u7a0b\u5e73\u9762\u56fe<\/p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px;\">\u8fd4\u56defactor Xa\u7684\u4e8b\u4f8b\uff0c\u6211\u4eec\u57283D\u6784\u9020\u4e2d\u770b\u4e00\u4e0b\u878d\u5408\u888b\u5b50\u7684\u90e8\u4f4d\uff08\u4e0b\u9762\u7684\u56fe\uff09\uff0c\u5f88\u663e\u8457\uff0c\u878d\u5408\u888b\u5b50\u5e76\u6ca1\u6709\u6df1\u5c42\u6b21\u86cb\u767d\u5167\u90e8\uff0c\u53cd\u800c\u662f\u5728\u6328\u8fd1\u6709\u673a\u6eb6\u5242\u6240\u53ca\u7684\u8868\u5c42\u3002\u5047\u5b9a\u6c92\u6709\u758f\u6c34\u6027\u7684\u5f02\u4e19\u57fa\u5360\u6709\uff0c\u758f\u6c34\u6027\u5185\u8154\u90e8\u4f4d\u5f88\u6709\u53ef\u80fd\u5360\u6709\u7740\u4e00\u4e9b\u6c34\u5206\uff0c\u4e00\u6837\u8fd9\u79cd\u5728\u4eb2\u6c34\u6027\u8868\u5c42\u7684\u6c34\u5206\u4f1a\u6108\u53d1\u7684\u4e95\u7136\u6709\u5e8f\u5176\u60c5\u51b5\u6570\u4f1a\u8f83\u5c11\uff0c\u8fdb\u800c\u5bf9\u7ed3\u5408\u81ea\u7531\u80fd\u6709\u4e0d\u597d\u7684\u5949\u732e\uff1b\u800c\u6839\u636e\u5f02\u4e19\u57fa\u53ef\u4ee5\u534f\u52a9\u6392\u51fa\u6765\u8fd9\u79cd\u6c34\u5206\uff0c\u8fdb\u800c\u5f97\u5230\u9664\u5f00\u4eb2\u6c34\u6027\u76f8\u4e92\u5f71\u54cd\u5916\u7684\u4e00\u90e8\u5206\u52a8\u80fd\uff0c\u56e0\u6b64\u6d3b\u529b\u88ab\u5927\u5927\u7684\u589e\u5f3a\u4e86[5\uff0c6]\u3002\u4ece\u8fd9\u4e00\u4e8b\u4f8b\u4e2d\u6211\u4eec\u53ef\u4ee5\u89c1\u5230\uff0c\u836f\u54c1\u8bbe\u8ba1\u65b9\u6848\u4e2d\u5927\u5bb6\u8fd8\u8981\u8003\u8651\u5230\u5728\u65e0\u914d\u4f4d\u878d\u5408\u60c5\u51b5\u4e0b\u878d\u5408\u888b\u5b50\u5f88\u6709\u53ef\u80fd\u7684\u6c34\u5316\u60c5\u51b5\uff01<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><\/p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px; text-align: center;\"><img decoding=\"async\" title=\"6.png\" src=\"\/wp-content\/uploads\/2021\/12\/20211215134559-61b9f1974fe68.png\" alt=\"6.png\" \/><\/p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px; text-align: center;\">\n<p style=\"margin-top: 0px; margin-bottom: 0px; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px;\"><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u56fe\u4e2d\u80fd\u591f\u770b\u89c12j4i\u4e2d\u7684\u914d\u4f4d\u878d\u5408\u888b\u5b50\u5728\u6328\u8fd1\u86cb\u6e05\u8868\u5c42\uff0c\u5904\u5728\u6709\u673a\u6eb6\u5242\u975e\u5e38\u5bb9\u6613\u8fdb\u5230\u7684\u5730\u533a\u3002\u9c9c\u7ea2\u8272\u90e8\u5206\u610f\u5473\u7740\u66dd\u9732\u6709\u673a\u6eb6\u5242\u4e2d\u7684\u5730\u533a\uff0c\u9752\u7eff\u8272\u610f\u5473\u7740\u4eb2\u6c34\u6027\u5730\u533a\uff0c\u7c89\u7ea2\u8272\u610f\u5473\u7740\u6b63\u8d1f\u6781\u5b98\u80fd\u56e2\u5730\u533a\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u7279\u522b\u6ce8\u610f\u7684\u662f\uff0c\u53bb\u6709\u673a\u6eb6\u5242\u5316\u4e5f\u662f\u6709\u5c06\u4f1a\u4f1a\u5bfc\u81f4\u770b\u4e0a\u53bb\u53ef\u4ee5\u6709\u6548\u5730\u4e0e\u86cb\u767d\u6fc0\u9176\u878d\u5408\u7684\u5206\u5b50\u7ed3\u6784\u5b9e\u9645\u4e0a\u5e76\u65e0\u6cd5\u6709\u6548\u5730\u878d\u5408\u3002\u4f8b\u5982\u5728\u4e00\u4e2a\u5bf9\u4e8eHIV-1\u86cb\u767d\u9176\u6291\u5236\u5242\u6297\u836f\u6027\u7684\u63a2\u8ba8\u4e2d\u53d1\u89c9\uff0c\u7531\u4e8e\u57fa\u56e0\u7a81\u53d8\u9020\u6210\u878d\u5408\u888b\u5b50\u7684\u53bb\u6709\u673a\u6eb6\u5242\u5316\u80fd\u660e\u663e\u63d0\u5347\uff0c\u8fdb\u800c\u81f4\u4f7f\u4e86\u6297\u836f\u6027[7]\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u518d\u4f8b\u5982\u5728\u6709\u55b9\u5511\u5549\u6bcd\u73af\u7684\u5316\u5b66\u7269\u8d28\u662f\u4e00\u7c7b\u5173\u952e\u7684EGFR\uff08epidermal growth factor receptor\uff0c\u5916\u76ae\u8f6c\u5316\u6210\u56e0\u7d20\u86cb\u767d\u6fc0\u9176\uff09\u7f13\u805a\u5242\uff0c\u5409\u975e\u66ff\u5c3c\u548c\u7279\u7f57\u51ef\u90fd\u5f52\u5c5e\u4e8e\u8be5\u7c7b\u836f\u3002\u4f8b\u5982\u4e0b\u9762\u7684\u56fe\u76842\u4e2a\u5316\u5b66\u7269\u8d28\uff0c\u4e0b\u5de6\u56fe\u4e3a\u77e5\u540d\u836f\u54c1\u7279\u7f57\u51ef\uff0c\u4e0b\u56fe\u4e3a\u5bdf\u89c9\u7684\u6b64\u5916\u4e00\u4e2a\u540c\u7cfb\u7684EGFR\u7f13\u805a\u5242\uff08\u59d1\u4e14\u79f0\u4e4b\u4e3a\u5316\u5b66\u7269\u8d28A\uff09[8]\u3002\u4e0b\u56fe\u5316\u5b66\u7269\u8d28A\u80fd\u4e0eEGFR \u7684Asp776\u4ea7\u751f\u79bb\u5b50\u952e\uff0c\u5927\u4f19\u513f\u4e86\u89e3\u79bb\u5b50\u952e\u80fd\u5230\u8fbe\u7684\u952e\u80fd\u662f\u8f83\u5f3a\u7684\uff0c\u7406\u8bba\u4e0a\uff0c\u4e0e\u7279\u7f57\u51ef\u5bf9\u6bd4\uff0c\u5316\u5b66\u7269\u8d28A\u7684\u6d3b\u529b\u63d0\u9ad8\u5e94\u5f53\u8fdc\u8fdc\u4e0d\u6b6210\u500d\u3002<br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" title=\"7.png\" src=\"\/wp-content\/uploads\/2021\/12\/20211215134559-61b9f1977351d.png\" \/><\/p>\n<p style=\"margin-top: 0px; margin-bottom: 0px; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px;\"><br style=\"font-family: \u5fae\u8f6f\u96c5\u9ed1, \u5b8b\u4f53\u5b57, \u9ed1\u4f53\u5b57, Arial, Helvetica, sans-serif; font-size: 16px;\" \/>\u56fe\u4e2d\u4e3a\u5316\u5b66\u7269\u8d28A\u548c\u7279\u7f57\u51ef\u7684\u53e0\u5408\u7d50\u679c\uff0c\u80fd\u591f\u770b\u89c1\u5316\u5b66\u7269\u8d28A\u80fd\u548cAsp776\u4ea7\u751f\u952e\u80fd\u6781\u5f3a\u7684\u79bb\u5b50\u952e\uff0c\u53ef\u662f\u6d3b\u529b\u5374\u53ea\u63d0\u9ad8\u4e8610\u500d\uff01\u5b9e\u9645\u4e0a\u8fd9\u4e5f\u662f\u56e0\u4e3a\u53bb\u6709\u673a\u6eb6\u5242\u5316\u80fd\u7684\u5371\u5bb3\uff0cAsp776\u5750\u843d\u4e8e\u6709\u673a\u6eb6\u5242\u6240\u53ca\u7684\u86cb\u6e05\u8868\u5c42\u4e0a\uff0c\u975e\u5e38\u5bb9\u6613\u4e0e\u6c34\u4ea7\u751f\u6bd4\u8f83\u5e73\u7a33\u7684\u5171\u4ef7\u952e\uff0c\u56e0\u800c\u8981\u4e0e-NH3 \u529f\u6548\u65f6\u52a1\u5fc5\u6446\u8131\u4e0e\u4e00\u4e9b\u6c34\u5206\u7684\u6548\u679c\u800c\u6d88\u8017\u4e00\u5b9a\u7684\u52a8\u80fd\u3002\u540c\u6837\uff0c\u5316\u5b66\u7269\u8d28A\u4e0a\u7684-NH3 \u4e5f\u662f\u4e00\u6837\u7684\uff0c\u5fc5\u987b\u65ad\u6389\u4e00\u90e8\u5206\u4e0e\u6c34\u4ea7\u751f\u7684\u5171\u4ef7\u952e\u53d6\u51b3\u4e8eAsp776\u7684\u7fa7\u57fa\u76f8\u4e92\u5f71\u54cd\u3002\u56e0\u800c\u770b\u8d77\u6765\u4ea7\u751f\u8f83\u5f3a\u7684\u5171\u4ef7\u952e\uff0c\u53ef\u662f\u56e0\u4e3a\u53bb\u6709\u673a\u6eb6\u5242\u5316\u7684\u529f\u6548\uff0c\u5176\u6d3b\u529b\u7684\u589e\u5f3a\u4e0d\u4e00\u5b9a\u6709\u60f3\u50cf\u4e2d\u7684\u7406\u60f3\u5316\u3002<\/p>\n<p style=\"text-align: center;\">\n<p>&nbsp;<\/p>\n<p><span style=\"font-size: 8pt; color: #999999;\"><em> \u8be5\u6587\u7ae0\u5185\u5bb9\u63d0\u9ad8\u6563\u64ad\u65b0\u6280\u672f\u5e94\u7528\u65b0\u95fb\u8d44\u8baf\uff0c\u5f88\u6709\u53ef\u80fd\u6709\u8f6c\u622a\/\u5f15\u5165\u4e4b\u72b6\u51b5\uff0c\u82e5\u6709\u4fb5\u6743\u884c\u4e3a\u8bf7\u8054\u7edc\u5220\u6389\u3002<\/em><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5927\u5bb6\u5e94\u8be5\u90fd\u77e5\u9053\u758f\u6c34\u6548\u5e94\uff08hydrophobiceffect\uff09\uff0c\u5373\u6c34\u6eb6\u6db2\u4e2d\u975e\u6781\u6027\u5206\u5b50\u6298\u53e0\u6216\u7f14\u5408\u7684\u73b0\u8c61\uff0c\u8bf4\u4eba\u8bdd\u5c31\u662f\uff0c\u6cb9\u4e0e\u6c34\u4e0d\u4e92\u6eb6\u3002\u758f\u6c34\u6548\u5e94\u8bf4\u8d77\u6765\u5f88\u7b80\u5355\u76f4\u89c2\uff0c\u4f46\u5b83\u5374\u662f\u4e2a\u72e0\u89d2\u8272\uff01\u6bd4\u5982\uff0c\u5728\u86cb\u767d\u6298\u53e0\u3001\u836f\u7269-\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\uff0c\u53ca\u86cb\u767d-\u86cb\u767d\u76f8\u4e92\u4f5c<\/p>\n","protected":false},"author":10,"featured_media":23668,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[59],"tags":[3613,3614,343,1433,1501,3612,3581],"class_list":["post-23669","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-information","tag-3613","tag-3614","tag-343","tag-1433","tag-1501","tag-3612","tag-3581"],"jetpack_featured_media_url":"\/wp-content\/uploads\/2021\/12\/20211215134559-61b9f197ada95.png","jetpack-related-posts":[{"id":16808,"url":"https:\/\/www.paiqinano.com\/?p=16808","url_meta":{"origin":23669,"position":0},"title":"\u738b\u709c\u3001\u66f9\u6bc5\u6559\u6388\u7814\u7a76\u56e2\u961f\u5728\u758f\u6c34\u76f8\u4e92\u4f5c\u7528\u65b9\u9762\u53d6\u5f97\u65b0\u8fdb\u5c55","author":"\u6d3e\u65d7\u7eb3\u7c73","date":"2022\u5e742\u670816\u65e5","format":false,"excerpt":"\u7269\u7406\u5b66\u9662\u738b\u709c\u6559\u6388\u3001\u66f9\u6bc5\u6559\u6388\u7814\u7a76\u56e2\u961f\u5728\u758f\u6c34\u76f8\u4e92\u4f5c\u7528\u7814\u7a76\u65b9\u9762\u53d6\u5f97\u65b0\u8fdb\u5c55\uff0c\u4ed6\u4eec\u53d1\u5c55\u4e86\u5355\u5206\u5b50\u529b\u8c31\u7684\u6d4b\u91cf\u65b9\u6cd5\uff0c\u2026","rel":"","context":"\u5728\u201c\u884c\u4e1a\u8d44\u8baf\u201d\u4e2d","block_context":{"text":"\u884c\u4e1a\u8d44\u8baf","link":"https:\/\/www.paiqinano.com\/?cat=59"},"img":{"alt_text":"","src":"\/wp-content\/uploads\/2021\/12\/20211215125837-61b9e67d210ad.jpg","width":350,"height":200},"classes":[]},{"id":11786,"url":"https:\/\/www.paiqinano.com\/?p=11786","url_meta":{"origin":23669,"position":1},"title":"[\u79d1\u8c31]\u4ec0\u4e48\u662f\u4eb2\u6c34\u6027\uff1f\u4ec0\u4e48\u662f\u758f\u6c34\u6027\uff1f\u4ec0\u4e48\u662f\u8d85\u758f\u6c34\u6027\uff1f","author":"\u6d3e\u65d7\u7eb3\u7c73","date":"2019\u5e743\u670814\u65e5","format":false,"excerpt":"\u5c0f\u79d1\u8c31\uff1a\u4ec0\u4e48\u662f\u4eb2\u6c34\u6027\u3001\u758f\u6c34\u6027\u3001\u4e0e\u8d85\u758f\u6c34\u6027 \u4ece\u7b80\u5355\u7684\u6570\u636e\u6765\u8bf4\uff0c\u4eb2\u6c34\u6027\u7684\u6c34\u63a5\u89e6\u89d2\u5c0f\u4e8e90\u5ea6\u3002\u758f\u6c34\u6027\u7684\u6c34\u63a5\u2026","rel":"","context":"\u5728\u201c\u4ea7\u54c1\u5feb\u8baf\u201d\u4e2d","block_context":{"text":"\u4ea7\u54c1\u5feb\u8baf","link":"https:\/\/www.paiqinano.com\/?cat=41"},"img":{"alt_text":"","src":"\/wp-content\/uploads\/2019\/03\/122.jpg","width":350,"height":200,"srcset":"\/wp-content\/uploads\/2019\/03\/122.jpg 1x, \/wp-content\/uploads\/2019\/03\/122.jpg 2x"},"classes":[]},{"id":26199,"url":"https:\/\/www.paiqinano.com\/?p=26199","url_meta":{"origin":23669,"position":2},"title":"\u758f\u51b0\u9632\u51b0\u6d82\u6599\u4e0e\u758f\u6c34\u618e\u6c34\u6d82\u6599\u5728\u98ce\u673a\u9632\u51b0\u5e94\u7528","author":"\u6d3e\u65d7\u7eb3\u7c73","date":"2021\u5e7412\u670818\u65e5","format":false,"excerpt":"\u6211\u56fd\u5730\u5927\u7269\u535a\u98ce\u573a\u8d44\u6e90\u4e30\u5bcc\uff0c\u98ce\u80fd\u5f00\u53d1\u6f5c\u529b\u5de8\u5927\uff0c\u4f46\u968f\u7740\u98ce\u80fd\u8d44\u6e90\u4e0d\u65ad\u7684\u6210\u719f\u4e0e\u5f00\u53d1\uff0c\u98ce\u573a\u7684\u4f4d\u7f6e\u6b63\u5728\u9010\u6e10\u5411\u7740\u98ce\u2026","rel":"","context":"\u5728\u201c\u884c\u4e1a\u8d44\u8baf\u201d\u4e2d","block_context":{"text":"\u884c\u4e1a\u8d44\u8baf","link":"https:\/\/www.paiqinano.com\/?cat=59"},"img":{"alt_text":"","src":"\/wp-content\/uploads\/2021\/12\/20211215142957-61b9fbe5db6c9.jpg","width":350,"height":200,"srcset":"\/wp-content\/uploads\/2021\/12\/20211215142957-61b9fbe5db6c9.jpg 1x, \/wp-content\/uploads\/2021\/12\/20211215142957-61b9fbe5db6c9.jpg 2x"},"classes":[]},{"id":23383,"url":"https:\/\/www.paiqinano.com\/?p=23383","url_meta":{"origin":23669,"position":3},"title":"\u5e72\u8d27\u5206\u4eab\uff1a\u77f3\u58a8\u70ef\u7684\u529f\u80fd\u5316\u6539\u6027\u2014\u758f\u6c34\u758f\u6cb9\u7bc7","author":"\u6d3e\u65d7\u7eb3\u7c73","date":"2021\u5e7412\u670830\u65e5","format":false,"excerpt":"\u77f3\u58a8\u70ef\u7531\u4e8e\u516d\u89d2\u82ef\u73af\u72b6\u7684\u77f3\u58a8\u70ef\u8868\u9762\u5177\u6709\u5f88\u9ad8\u7684\u5316\u5b66\u7a33\u5b9a\u6027\uff0c\u4e0e\u5176\u4ed6\u4ecb\u8d28\u76f8\u4e92\u4f5c\u7528\u529b\u5f88\u5f31\uff0c\u4e14\u7247\u5c42\u4e4b\u95f4\u7684\u51e1\u5f97\u74e6\u529b\u2026","rel":"","context":"\u5728\u201c\u884c\u4e1a\u8d44\u8baf\u201d\u4e2d","block_context":{"text":"\u884c\u4e1a\u8d44\u8baf","link":"https:\/\/www.paiqinano.com\/?cat=59"},"img":{"alt_text":"","src":"\/wp-content\/uploads\/2021\/12\/20211215134032-61b9f050cce51.png","width":350,"height":200},"classes":[]},{"id":16477,"url":"https:\/\/www.paiqinano.com\/?p=16477","url_meta":{"origin":23669,"position":4},"title":"\u4f4e\u8868\u9762\u80fd\u8d85\u758f\u6c34\u6d82\u5c42\u7406\u8bba\u6a21\u578b\u53ca\u539f\u7406","author":"\u6d3e\u65d7\u7eb3\u7c73","date":"2022\u5e741\u670819\u65e5","format":false,"excerpt":"\u758f\u6c34\u6d82\u6599\u7684\u7406\u8bba\u6a21\u578b\u6db2\u4f53\u5728\u56fa\u4f53\u8868\u9762\u7684\u6da6\u6e7f\u7279\u6027\u5e38\u7528\u6768\u6c0f\u65b9\u7a0b\u63cf\u8ff0\u3002\u6db2\u6ef4\u4e0e\u56fa\u4f53\u8868\u9762\u7684\u63a5\u89e6\u89d2\u5927\uff0c\u6da6\u6e7f\u6027\u5dee\uff0c\u5176\u758f\u2026","rel":"","context":"\u5728\u201c\u884c\u4e1a\u8d44\u8baf\u201d\u4e2d","block_context":{"text":"\u884c\u4e1a\u8d44\u8baf","link":"https:\/\/www.paiqinano.com\/?cat=59"},"img":{"alt_text":"","src":"\/wp-content\/uploads\/2021\/12\/20211215125706-61b9e622cd515.jpg","width":350,"height":200,"srcset":"\/wp-content\/uploads\/2021\/12\/20211215125706-61b9e622cd515.jpg 1x, \/wp-content\/uploads\/2021\/12\/20211215125706-61b9e622cd515.jpg 2x, \/wp-content\/uploads\/2021\/12\/20211215125706-61b9e622cd515.jpg 3x"},"classes":[]},{"id":25801,"url":"https:\/\/www.paiqinano.com\/?p=25801","url_meta":{"origin":23669,"position":5},"title":"\u4f4e\u8868\u9762\u80fd\u8d85\u758f\u6c34\u6d82\u5c42\u7406\u8bba\u6a21\u578b\u53ca\u539f\u7406","author":"\u6d3e\u65d7\u7eb3\u7c73","date":"2021\u5e7412\u670819\u65e5","format":false,"excerpt":"\u758f\u6c34\u6d82\u6599\u7684\u7406\u8bba\u6a21\u578b\u6db2\u4f53\u5728\u56fa\u4f53\u8868\u9762\u7684\u6da6\u6e7f\u7279\u6027\u5e38\u7528\u6768\u6c0f\u65b9\u7a0b\u63cf\u8ff0\u3002\u6db2\u6ef4\u4e0e\u56fa\u4f53\u8868\u9762\u7684\u63a5\u89e6\u89d2\u5927\uff0c\u6da6\u6e7f\u6027\u5dee\uff0c\u5176\u758f\u2026","rel":"","context":"\u5728\u201c\u884c\u4e1a\u8d44\u8baf\u201d\u4e2d","block_context":{"text":"\u884c\u4e1a\u8d44\u8baf","link":"https:\/\/www.paiqinano.com\/?cat=59"},"img":{"alt_text":"","src":"\/wp-content\/uploads\/2021\/12\/20211215142311-61b9fa4f6e13d.jpg","width":350,"height":200},"classes":[]}],"_links":{"self":[{"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=\/wp\/v2\/posts\/23669","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=\/wp\/v2\/users\/10"}],"replies":[{"embeddable":true,"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23669"}],"version-history":[{"count":2,"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=\/wp\/v2\/posts\/23669\/revisions"}],"predecessor-version":[{"id":26990,"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=\/wp\/v2\/posts\/23669\/revisions\/26990"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=\/wp\/v2\/media\/23668"}],"wp:attachment":[{"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23669"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23669"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.paiqinano.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23669"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}